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Published on: August 15, 2019
The conservation of gene models can support genome annotation
Cassandria G Tay Fernandez1, Philipp E Bayer1, Jakob Petereit1
1School of Biological Sciences and Institute of Agriculture, University of Western Australia, Perth, Western Australia, Australia.
Abstract:
Many genome annotations include false-positive gene models, leading to errors in phylogenetic and comparative studies. Here, we propose a method to support gene model prediction based on evolutionary conservation and use it to identify potentially erroneous annotations. Using this method, we developed a set of 15,345 representative gene models from 12 legume assemblies that can be used to support genome annotations for other legumes.
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