Related Experiment Video
Updated: Jul 22, 2026
16:11
Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
35.3K
A Novel Pumping Principle for a Total Artificial Heart
IEEE Transactions on Bio-Medical Engineering
|August 21, 2023
Summary
This study demonstrates a novel valveless pumping principle for a total artificial heart (TAH). The ShuttlePump shows feasibility for durable cardiac replacement, addressing limitations of current TAH devices.
Area of Science:
- Biomedical Engineering
- Cardiovascular Devices
- Medical Technology
Background:
- Current total artificial hearts (TAH) face durability and complication issues, limiting long-term use.
- Severe biventricular heart failure necessitates advanced cardiac replacement solutions.
Purpose of the Study:
- To assess the feasibility of a novel valveless pumping principle for a durable pulsatile TAH, named ShuttlePump.
- To evaluate the performance and hemocompatibility of the ShuttlePump design.
Main Methods:
- Iterative design using analytical, in silico (FEM, CFD) methods.
- Experimental evaluation in a mock circulation loop.
- Numerical calculation of hemocompatibility parameters.
Main Results:
- The ShuttlePump covers the full TAH operating range (2.5-9 L/min flow, 50-160 mmHg pressure).
- Low energy losses (<2 K blood temperature rise) and good hemocompatibility (index of hemolysis 3.57 mg/100 L) were observed.
- Efficient blood volume exchange (95% in 1.42 s) was achieved.
Conclusions:
- The ShuttlePump's novel valveless pumping principle is feasible for TAH applications.
- Numerical and experimental results support further development of this durable TAH system.
