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Calprotectin: two sides of the same coin
Valeria Carnazzo1, Serena Redi1,2, Valerio Basile3
1Department of Clinical Pathology, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Rheumatology (Oxford, England)
|August 21, 2023
Summary
Circulating calprotectin (CLP) shows promise as a biomarker in autoimmune diseases. Measuring serum CLP may help monitor disease progression and outcomes in various autoimmune conditions.
Area of Science:
- Biochemistry
- Immunology
- Clinical Diagnostics
Background:
- Calprotectin (CLP) is an inflammatory protein primarily known for its role in inflammatory bowel disease (IBD).
- Recent research focuses on circulating CLP in biological fluids beyond feces, including blood, saliva, and urine.
Conclusions:
- Circulating calprotectin is a relevant molecule in autoimmune diseases.
- Serum CLP measurement shows potential as a biomarker for monitoring disease outcomes.
- Further research may establish CLP as a valuable tool in managing autoimmune conditions.

