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Updated: Jul 18, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
The Medicare Appropriate Use Criteria Program: A Review of Recommendations for Testing in Coronary Artery Disease
David E Winchester1, Friederike K Keating2, Krishna K Patel3
1Malcom Randall VAMC and University of Florida College of Medicine, Gainesville, Florida (D.E.W.).
Background:
Congress established the Appropriate Use Criteria (AUC) Program to reduce unnecessary advanced imaging studies. Organizations that wish to develop AUC can apply to the Centers for Medicare & Medicaid Services (CMS) to qualify as provider-led entities (PLEs) under this program. Variable methods, content, and formatting of PLE-generated AUC could lead to clinician uncertainty about whether an advanced imaging test is appropriate or not.
Purpose:
To review AUC published by CMS-qualified PLEs focused on advanced imaging tests for coronary artery disease (CAD), a "priority clinical area" identified by CMS.
Data Sources:
Publicly available data from the worldwide web searched on 29 August 2022.
Study Selection:
Approved AUC with recommendations related to testing for CAD.
Data Extraction:
Manual review of published AUC by all authors.
Data Synthesis:
Among the 17 CMS-qualified PLEs, only 7 had published AUC related to CAD. Substantial variation in the methods and formatting of these AUCs was observed. The number of clinical scenarios covered ranged from 6 to 210, and the number of advanced imaging methods covered ranged from 1 to 25. When specifically applied to clinical scenarios, many AUC offered no guidance on appropriateness; those that did conflicted with respect to appropriateness.
Limitation:
Other CMS-identified priority clinical areas were not evaluated.
Conclusion:
CMS-qualified AUC for imaging of CAD are heterogeneous and sometimes discrepant, creating substantial potential for uncertainty among clinicians seeking to provide their patients with appropriate imaging tests.
Primary Funding Source:
No funding was received for this study.
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