Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Confocal Fluorescence Microscopy

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>HER-2</i> gene alterations as biomarker in patients with metastatic colorectal cancer treated with FOLFIRI + cetuximab: findings from the CAPRI-2 GOIM study.

ESMO gastrointestinal oncology·2026

Same author

Clinical and translational results from the phase II ABACO trial evaluating the activity of cabozantinib in pretreated patients with metastatic colorectal cancer.

ESMO gastrointestinal oncology·2026

Same author

Off-label drug use in oncology: integrating molecular and genetic analysis in an academic center's real-world approach.

ESMO real world data and digital oncology·2026

Same author

ItaLynch: an ongoing Italian study to evaluate the feasibility of mainstreaming the diagnosis of Lynch syndrome in colorectal cancer patients.

ESMO gastrointestinal oncology·2026

Same author

Cetuximab rechallenge in molecularly selected metastatic colorectal cancer: the randomized CAVE-2 GOIM trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2025

Same author

Genomic profiling of high tumor mutational load in microsatellite-stable colorectal cancer uncovers MAPK signaling pathway alterations following anti-EGFR therapy.

ESMO open·2025

Search research articles

Related Experiment Video

Updated: Jul 18, 2025

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

Solving classification tasks by a receptron based on nonlinear optical speckle fields.

B Paroli¹, G Martini¹, M A C Potenza¹

¹CIMAINA and Dipartimento di Fisica, Università degli Studi di Milano, via G. Celoria 16, 20133, Milan, Italy.

Neural Networks : the Official Journal of the International Neural Network Society

|August 21, 2023

Summary

This summary is machine-generated.

Researchers developed a new "receptron" model for neuromorphic computing, offering advantages over traditional perceptrons for solving complex problems using optical hardware.

Keywords:

Boolean functions Classification Non-linear networks Optical device Perceptron

More Related Videos

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Published on: August 5, 2009

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

Related Experiment Videos

Last Updated: Jul 18, 2025

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

Published on: August 5, 2009

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

Area of Science:

Neuromorphic Computing
Optical Computing
Artificial Intelligence Hardware

Background:

Energy consumption in computing is a major challenge.
Photonic artificial neural networks (ANNs) and nanoscale junction networks are explored for neuromorphic computing.
These networks exhibit emergent complexity, self-organization, and non-linearity, mimicking biological neural networks.

Purpose of the Study:

To propose and formalize a generalized perceptron model called "receptron".
To demonstrate the receptron's advantages in solving complex computational problems.
To implement an all-optical device based on the receptron model for efficient data processing.

Main Methods:

Formalization of the receptron model with non-linearly dependent input weights.
Implementation of an all-optical device utilizing the non-linearity of optical speckle fields.
Encoding speckle fields to generate diverse Boolean functions for classification tasks.

Main Results:

The receptron model solves non-linearly separable Boolean functions with a single device, outperforming the standard perceptron.
Efficiently solved various classes of Boolean functions by adjusting model parameters.
Demonstrated the feasibility of an all-optical implementation for neuromorphic data processing.

Conclusions:

The receptron model offers significant advantages for classification tasks compared to traditional perceptrons.
The all-optical implementation provides a pathway for novel, simple hardware for neuromorphic computing.
This research opens new avenues for energy-efficient optical data processing.