Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

53.6K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.6K
Visual System01:26

Visual System

616
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
616
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

4.0K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.0K
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

718
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
718
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

7.2K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Richness of Vision in the Mammalian Brain: Neural Codes for Visual Perception and Behavior in Three Dimensions.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025
Same author

Genetically defined neuron types underlying visuomotor transformation in the superior colliculus.

Nature reviews. Neuroscience·2024
Same author

Transformation of Motion Pattern Selectivity from Retina to Superior Colliculus.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2024
Same author

Maternal diet during early gestation influences postnatal taste activity-dependent pruning by microglia.

The Journal of experimental medicine·2023
Same author

Neural circuits for binocular vision: Ocular dominance, interocular matching, and disparity selectivity.

Frontiers in neural circuits·2023
Same author

Strong tuning for stereoscopic depth indicates orientation-specific recurrent circuitry in tree shrew V1.

Current biology : CB·2022
Same journal

Endogenous peptide derived from c-Cbl-associated protein counteracts its inhibitory effect on enteric neural crest cell colonization in Hirschsprung disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Drowsiness alters the neural dynamics but not the core computations of multisensory integration.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

A Matter of Parameters: Tailored Transcranial Focused Ultrasound Enhances Cortico-Thalamo-Cortical Circuit Resonance.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Proactive visual and motor prioritization differentially scale with cue reliability.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Erratum: Yao et al., "Estrogen Regulates Bcl-w and Bim Expression: Role in Protection against β-Amyloid Peptide-Induced Neuronal Death".

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Erratum: L'Episcopo et al., "Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/β-Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair".

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

10.0K

Widespread and Multifaceted Binocular Integration in the Mouse Primary Visual Cortex.

Jieming Fu1,2, Seiji Tanabe3, Jianhua Cang4,3

  • 1Neuroscience Graduate Program.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|August 21, 2023
PubMed
Summary
This summary is machine-generated.

Brain circuits perform binocular integration for 3D vision. This study reveals widespread, independent integration in mouse V1, challenging simple models and highlighting intracortical circuit roles in visual processing.

Keywords:
binocular visionbinocularityorientation selectivitysensory integrationstereopsisstereoscopic vision

More Related Videos

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

4.5K
Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

11.3K

Related Experiment Videos

Last Updated: Jul 18, 2025

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

10.0K
Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

4.5K
Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

11.3K

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Visual Processing

Background:

  • The brain integrates 2D images from two eyes into a 3D percept.
  • Primary visual cortex (V1) binocular integration models neural circuit emergent properties.

Purpose of the Study:

  • To characterize binocular integration in mouse V1.
  • To investigate the independence of ocular dominance, interocular matching, and disparity selectivity.
  • To evaluate existing models of binocular integration.

Main Methods:

  • Electrophysiological recordings in awake adult male and female mice.
  • Systematic variation of monocular and binocular stimulus orientation and phase disparity.
  • Analysis of neuronal responses across cortical layers and neuron types.

Main Results:

  • Widespread binocular integration observed in mouse V1.
  • Ocular dominance, interocular matching, and disparity selectivity were found to be independent.
  • Monocular response amplitude predicted binocular response amplitude, but not selectivity.
  • Binocular integration is extensive and independent across cortical layers and neuron types.

Conclusions:

  • Simple feedforward convergence models are inadequate for V1 binocular integration.
  • Intracortical circuits play a crucial role in binocular computation and disparity processing.
  • Findings suggest plasticity in brain circuits for binocular development and processing.