Related Experiment Video
Updated: Jul 18, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
An active learning machine technique based prediction of cardiovascular heart disease from UCI-repository database
Saravanan Srinivasan1, Subathra Gunasekaran2, Sandeep Kumar Mathivanan3
1Department of Computer Science and Engineering, Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and Technology, Avadi, Chennai, India.
Abstract:
Heart disease is a significant global cause of mortality, and predicting it through clinical data analysis poses challenges. Machine learning (ML) has emerged as a valuable tool for diagnosing and predicting heart disease by analyzing healthcare data. Previous studies have extensively employed ML techniques in medical research for heart disease prediction. In this study, eight ML classifiers were utilized to identify crucial features that enhance the accuracy of heart disease prediction. Various combinations of features and well-known classification algorithms were employed to develop the prediction model. Neural network models, such as Naïve Bayes and Radial Basis Functions, were implemented, achieving accuracies of 94.78% and 90.78% respectively in heart disease prediction. Among the state-of-the-art methods for cardiovascular problem prediction, Learning Vector Quantization exhibited the highest accuracy rate of 98.7%. The motivation behind predicting Cardiovascular Heart Disease lies in its potential to save lives, improves health outcomes, and allocates healthcare resources efficiently. The key contributions encompass early intervention, personalized medicine, technological advancements, the impact on public health, and ongoing research, all of which collectively work toward reducing the burden of CHD on both individual patients and society as a whole.
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