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Bioelectrical impedance analysis in patients with posterior vitreous detachment
E Di Marco1, M Di Marino, M Lombardo
1Department of Experimental Medicine, Ophthalmology Unit, University of Rome Tor Vergata, Rome, Italy. Ernesto2601@hotmail.it.
Insights
This study found that body hydration levels, measured by bioelectrical impedance analysis (BIA), correlate with the severity of posterior vitreous detachment (PVD). Patients with partial PVD showed different hydration markers compared to those with complete PVD.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Human Physiology
Background:
- Posterior vitreous detachment (PVD) is a common condition often anecdotally linked to reduced water intake.
- Scientific literature lacks robust evidence supporting the association between PVD and decreased hydration.
- Assessing body hydration is crucial for understanding overall patient health and disease progression.
Purpose of the Study:
- To evaluate body hydration status in patients diagnosed with posterior vitreous detachment (PVD).
- To investigate the relationship between the degree of PVD and body composition parameters.
- To utilize bioelectrical impedance analysis (BIA) as a non-invasive method for hydration assessment in PVD patients.
Main Methods:
- Patients with PVD were categorized into partial (P-PVD) and complete (C-PVD) groups based on Spectral Domain Optical Coherence Tomography (SD-OCT).
- Bioelectrical impedance analysis (BIA) was performed to measure parameters including Resistance (R), Reactance (Xc), Total Body Water (TBW), and Extracellular Water (ECW).
- A cohort of 30 patients (12 P-PVD, 18 C-PVD) completed BIA measurements and a floaters symptoms questionnaire.
Main Results:
- Lower values of Resistance (R) and Reactance (Xc) were observed in the P-PVD group compared to the C-PVD group.
- Patients in the P-PVD group exhibited higher Total Body Water (TBW) and Extracellular Water (ECW) than those in the C-PVD group.
- Statistical analysis revealed significant differences in BIA parameters between the P-PVD and C-PVD patient groups.
Conclusions:
- The study demonstrates a significant correlation between the pathological state of the vitreous and anthropometric and bioelectrical impedance analysis measurements.
- Findings suggest that hydration status, as assessed by BIA, may be associated with the stage of posterior vitreous detachment.
- Further research is warranted to elucidate the complex relationship between PVD and body composition.
Objective:
The purpose of the study is to assess body hydration in patients with posterior vitreous detachment (PVD) by bioelectrical impedance analysis (BIA). PVD, one of the most common eye diseases, is associated in both research and the collective image with reduced daily water intake, but this finding is not supported by strong evidence in the literature.
Patients And Methods:
Based on Spectral Domain Optical Coherence Tomography (SD-OCT) evaluation, different PVD stages are identified: absent posterior vitreous detachment, partial posterior vitreous detachment (P-PVD), or complete posterior vitreous detachment (C-PVD). BIA is a simple, non-invasive bedside method used to assess body composition. Patients underwent BIA and completed a floaters symptoms. 30 patients were enrolled and divided into two groups according to the degree of vitreous detachment, in P-PVD (n=12) and C-PVD (n=18). Patients underwent BIA and completed a floaters symptoms questionnaire. BIA measured the Resistance (R), Reactance (Xc), Phase Angle (PhA), Total Body Water (TBW), Extracellular Water (ECW), Fat Mass (FM), Fat-Free Mass (FFM), and Body Cell Mass Index (BCMI). Finally, patients received a test to assess adherence to the Mediterranean diet (Mediterranean Diet Test Score, MDTS) with the addition of daily water intake.
Results:
Relevant data were obtained from the BIA evaluation: the values of R and Xc were lower in the P-PVD group than C-PVD group (respectively 417.08±58.12 Ω vs. 476.94±51.29 Ω p=0.006 and 41.33±8.23 Ω vs. 50.61±7.98 Ω p=0.004). Instead, patients in the P-PVD group reported higher values of TBW and ECW than C-PVD group (respectively 44.13±7.57 L vs. 37.96±6.27 L p=0.021 and 21.03±4.06 L vs. 17.24±2.63 L p=0.004).
Conclusions:
In the present study, we reported a significant correlation between vitreous pathology and anthropometric and BIA measurements.
