Two-stage or not two-stage? That is the question for IPD meta-analysis projects

Richard D Riley1, Joie Ensor1, Miriam Hattle1,2

  • 1Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

PubMed
Summary

Individual participant data meta-analysis (IPDMA) requires choosing between one-stage and two-stage approaches. The one-stage method is preferred for small studies, while the two-stage approach is often sufficient for most researchers.

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