Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing Fat Graft Survival with Poly-L-Lactic Acid: An Experimental Study in Wistar Rats.

Aesthetic plastic surgery·2026
Same author

Non-surgical Treatment and Prophylaxis of Capsular Contracture in Mammary Implants: A Systematic Review of Literature.

Aesthetic plastic surgery·2025
Same author

The efficacy of arterial only microsurgical nasal replantation: a systematic review.

ANZ journal of surgery·2024
Same author

A microscope in your pocket: can smartphones be used to perform microsurgery?

Acta cirurgica brasileira·2024
Same author

Finesse in Fleur-de-lis Abdominoplasty.

Clinics in plastic surgery·2023
Same author

Use of Phosphodiesterase Inhibitors in the Postoperative Period of Skin Flaps: A Systematic Review.

Plastic and reconstructive surgery. Global open·2023

Related Experiment Video

Updated: Jul 18, 2025

Author Spotlight: Unveiling the Therapeutic Effects of FSN Treatment – Bridging Research and Clinical Applications in Neuropathic Pain
08:20

Author Spotlight: Unveiling the Therapeutic Effects of FSN Treatment – Bridging Research and Clinical Applications in Neuropathic Pain

Published on: June 30, 2023

2.0K

Nerve Injury and Peripheral Nerve Functional Loss From Injection and Suture Needles: An Experimental Study on Rats.

Matheus Scuracchio Fernandes, Fausto Viterbo, Lorena Delgado Rodrigues

    Aesthetic Surgery Journal
    |August 22, 2023
    PubMed
    Summary

    Needle-based procedures like injections and sutures are safe for peripheral nerves. Studies show no significant nerve impairment or functional loss from these common medical interventions.

    More Related Videos

    Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat
    12:09

    Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat

    Published on: April 18, 2020

    12.2K
    Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
    04:34

    Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

    Published on: January 25, 2022

    4.9K

    Related Experiment Videos

    Last Updated: Jul 18, 2025

    Author Spotlight: Unveiling the Therapeutic Effects of FSN Treatment – Bridging Research and Clinical Applications in Neuropathic Pain
    08:20

    Author Spotlight: Unveiling the Therapeutic Effects of FSN Treatment – Bridging Research and Clinical Applications in Neuropathic Pain

    Published on: June 30, 2023

    2.0K
    Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat
    12:09

    Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat

    Published on: April 18, 2020

    12.2K
    Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
    04:34

    Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

    Published on: January 25, 2022

    4.9K

    Area of Science:

    • Neuroscience
    • Surgical Research
    • Experimental Pathology

    Background:

    • Peripheral nerve damage can occur during invasive procedures.
    • A reliable experimental model is needed to study these risks.

    Purpose of the Study:

    • To evaluate peripheral nerve lesions from needle entry/exit, suture transfixion, and injections.
    • To assess the safety of common procedural elements on nerve integrity.

    Main Methods:

    • 36 Wistar rats were divided into control, sham, suture, needle, saline, and lidocaine groups.
    • Functional walking analysis, electrophysiological studies, and histological analysis were performed.
    • Procedures simulated needle trauma and local anesthetic/saline injections in rat paws.

    Main Results:

    • All groups demonstrated normalized walking function within 13 days.
    • Minimal histological changes were observed across all experimental groups.
    • No significant functional loss was detected in relation to the simulated procedures.

    Conclusions:

    • Infusion of local anesthetics or saline solutions is safe for peripheral nerve function.
    • Suture needles and accidental needle-related events do not typically cause nerve impairment.
    • Experimental simulation indicates low risk of nerve damage from these procedures.