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Related Concept Videos

Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

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Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
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Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

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Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
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Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

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Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
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Mechanism of Cardiac Arrhythmias01:28

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

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Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
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Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

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Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
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Related Experiment Video

Updated: Jul 18, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Managing arrhythmia in cardiac resynchronisation therapy.

Felicity de Vere1,2, Nadeev Wijesuriya1,2, Mark K Elliott1,2

  • 1School of Biomedical Engineering and Imaging Sciences, King's College, London, United Kingdom.

Frontiers in Cardiovascular Medicine
|August 23, 2023
PubMed
Summary
This summary is machine-generated.

Arrhythmia management is crucial in cardiac resynchronisation therapy (CRT) patients to optimize biventricular pacing (BVP). This review explores strategies for controlling atrial and ventricular arrhythmias in CRT recipients.

Keywords:
AF ablationAV node ablationarrhythmia (any)atrial fibillationcardiac resynchronisation therapy (CRT)heart failuresupraventricular arrhythmiasventricular arrhythmia (VAs)

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Arrhythmias are common in patients undergoing cardiac resynchronisation therapy (CRT).
  • Exclusion of patients with recent arrhythmias in major CRT trials limits evidence-based management.
  • Existing knowledge on arrhythmia management is primarily derived from heart failure (HF) trials, not specific to CRT.

Purpose of the Study:

  • To review the impact of atrial and ventricular arrhythmias on CRT efficacy.
  • To discuss optimal arrhythmia management strategies in the CRT population.
  • To explore novel methods for arrhythmia treatment guided by device data.

Main Methods:

  • Literature review of randomized trials and observational studies.
  • Analysis of pharmacological and procedural interventions for arrhythmia control.
  • Exploration of device data utilization for treatment guidance.

Main Results:

  • Arrhythmias significantly interfere with optimal biventricular pacing (BVP) delivery in CRT patients.
  • Effective arrhythmia management is essential for maximizing HF outcomes in CRT recipients.
  • A greater incentive exists to control arrhythmias in CRT patients compared to the general HF population.

Conclusions:

  • Optimal arrhythmia management is critical for successful CRT.
  • Pharmacological, procedural, and device-based strategies are key to controlling arrhythmias in CRT patients.
  • Leveraging device data offers promising avenues for personalized arrhythmia treatment in CRT.