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Updated: Jul 18, 2025

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Optimizing aortic valve prosthesis selection in patients with obesity: Institutional experience with
Ozan Onur Balkanay1, Halil Ibrahim Bulut2, Ergida Albrahimi1
1Department of Cardiovascular Surgery Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Insights
For obese patients undergoing aortic valve replacement, neither bioprosthetic nor mechanical valves showed significant differences in outcomes. Careful consideration of valve choice is still recommended for this population.
Area of Science:
- Cardiology
- Surgical Innovation
- Obesity Medicine
Background:
- Aortic valve diseases are prevalent and life-threatening, with obesity as a significant risk factor.
- Current guidelines lack specific management strategies for aortic valve disease in obese patients.
- The optimal choice of prosthetic valve in obese individuals remains unclear.
Purpose of the Study:
- To compare the outcomes of bioprosthetic versus mechanical aortic valve replacement in patients with obesity.
- To evaluate perioperative characteristics and follow-up results in this specific patient cohort.
Main Methods:
- A total of 130 obese patients underwent surgical aortic valve replacement.
- Patients were divided into two groups: 50 received bioprosthetic valves, and 80 received mechanical valves.
- Perioperative characteristics and follow-up results were compared between the groups.
Main Results:
- No significant differences were observed in patient demographics, preoperative conditions, or intraoperative characteristics between the bioprosthetic and mechanical valve groups.
- Postoperative outcomes, including mortality and acute kidney injury, did not significantly differ between the groups.
- Intensive care unit (ICU) stays were shorter for bioprosthetic valve recipients, though not statistically significant.
Conclusions:
- Valve selection for obese patients, especially those with class II obesity, requires careful consideration.
- Obesity's impact on valve choice and the potential for future bariatric surgery should be factored into decisions.
Background:
Aortic valve diseases are life-threatening conditions with increasing prevalence worldwide. Risk factors include gender, age, hypertension, dyslipidemia, and type 2 diabetes. Obesity is closely related to these risk factors and has been linked to a higher risk of developing aortic valve diseases. However, there is no specific guideline for managing aortic valve disease in patients with obesity, and the choice of valve type remains uncertain.
Methods:
A total of 130 patients with obesity who met the inclusion criteria underwent surgical aortic valve replacement. The patients were divided into two groups based on the type of prosthesis used. Among the study cohort, 50 patients received a bioprosthetic valve, while 80 patients received a mechanical valve. We compared these groups in terms of perioperative characteristics and follow-up results. Statistical significance was determined using a p-value threshold of 0.05.
Results:
There were no significant differences in age, gender, body mass index, or cardiac comorbidities between the two groups. Preoperative blood results and echo findings also showed no significant differences. Intraoperative characteristics and postoperative outcomes, including mortality and acute kidney injury, did not differ significantly between the groups. In addition, BHVG patients had shorter ICU stays compared to MHVG patients without significance.
Conclusion:
Deliberate consideration is crucial when selecting valves for obese patients, particularly those with class II obesity. This is due to the potential influence of obesity on valve types, as well as the need to account for the possibility of bariatric surgery and its potential effects.
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