Innovative i-PRF semisurgical method for gingival augmentation and root coverage in thin periodontal phenotypes: a...

Area of Science:

• Periodontology
• Regenerative Dentistry
• Biomaterials

Background:

• Thin periodontal phenotypes are associated with increased risk of gingival recession and complications.
• Gingival augmentation techniques aim to improve periodontal health and aesthetics.
• Injectable platelet-rich fibrin (i-PRF) is an autologous blood concentrate rich in growth factors.

Purpose of the Study:

• To evaluate the efficacy of injectable platelet-rich fibrin (i-PRF) in increasing gingival thickness.
• To assess the impact of i-PRF on reducing gingival recession in patients with thin periodontal phenotypes.
• To explore the potential of i-PRF in periodontal tissue regeneration.

Main Methods:

• A prospective study involving 53 tooth regions with thin periodontal phenotypes.
• Application of i-PRF using a semisurgical technique with minimal incision and periosteal elevation.
• Four i-PRF injection sessions at 10-day intervals to ensure sustained exposure to growth factors.

Main Results:

• Increased gingival thickness was observed in 92.5% of treated areas, with 44.9% achieving the target thickness of 0.8 mm.
• Significant reduction in gingival recession was noted in 83.3% of treated recession areas (P = .005).
• Complete root coverage was achieved in 60% of the gingival recession sites.

Conclusions:

• The semisurgical i-PRF method effectively enhances gingival thickness and addresses gingival recession in thin periodontal phenotypes.
• i-PRF demonstrates potential for promoting angiogenesis and improving histoconductive properties in periodontal regeneration.
• Further research is warranted to fully elucidate the mechanisms and long-term outcomes of i-PRF in periodontal therapy.