Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lifestyle Factors and Health01:20

Lifestyle Factors and Health

75
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
75
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

142
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
142
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

266
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
266
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

119
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
119
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

1.6K
The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results...
1.6K
Models of Health Promotion and Illness Prevention I01:25

Models of Health Promotion and Illness Prevention I

2.1K
A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term Cancer Risk in Acromegaly: A Population-Based Cohort Study with 44 Years of Follow-up.

European journal of endocrinology·2026
Same author

Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder: A Systematic Review and Meta-Analysis.

The Journal of clinical psychiatry·2026
Same author

Effect of an Online, Interactive Lifestyle Intervention Program on 12-Month Disease Management Outcomes: Protocol for The Healthy Living in Inflammatory Arthritis (HELIA) Randomized Controlled Trial.

JMIR research protocols·2026
Same author

Distinct plasma protein profiles after long-term remission of Cushing's disease.

The Journal of clinical endocrinology and metabolism·2026
Same author

Why Analyses of Achieved Sodium Correction Rates in Hyponatremia Studies Do Not Identify Causal (Treatment) Effects.

Journal of the American Society of Nephrology : JASN·2026
Same author

Discontinuation of Levothyroxine in Adults Aged 60 Years or Older.

JAMA·2026

Related Experiment Video

Updated: Jul 18, 2025

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.4K

[Challenges for evaluating complex interventions: The example of lifestyle].

Olaf M Dekkers1,2, Nathalie Wilmsen3, Willem Geerlings3

  • 1Leids Universitair Medisch Centrum, afd. Interne Geneeskunde.

Nederlands Tijdschrift Voor Geneeskunde
|August 23, 2023
PubMed
Summary
This summary is machine-generated.

Evaluating lifestyle interventions for chronic diseases like diabetes and obesity requires robust research. While randomized controlled trials (RCTs) are standard, non-randomized studies can offer valid evidence under specific conditions.

More Related Videos

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.2K
Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

6.8K

Related Experiment Videos

Last Updated: Jul 18, 2025

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.4K
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.2K
Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

6.8K

Area of Science:

  • Public Health
  • Preventive Medicine
  • Clinical Research Methodology

Background:

  • Lifestyle interventions are crucial for managing chronic diseases like type 2 diabetes and obesity.
  • The effectiveness of lifestyle interventions is often not rigorously evaluated using standard research methods.
  • Randomized controlled trials (RCTs) are considered the gold standard for drug research but present challenges for lifestyle interventions.

Purpose of the Study:

  • To discuss the methodological challenges of using RCTs for lifestyle interventions.
  • To explore alternative research methodologies for evaluating lifestyle interventions.
  • To assess the validity of non-randomized clinical trials in this field.

Main Methods:

  • Discussion of methodological limitations of RCTs in lifestyle intervention research.
  • Exploration of non-randomized clinical trial designs.
  • Analysis of 'real world' research for evidence generation.

Main Results:

  • RCTs face significant methodological hurdles when applied to lifestyle interventions.
  • Non-randomized clinical trials, when carefully designed, can provide valid evidence.
  • Real-world research offers a viable alternative for assessing lifestyle interventions.

Conclusions:

  • The application of RCTs to lifestyle interventions is methodologically complex.
  • Carefully designed non-randomized studies are valuable for evaluating lifestyle interventions.
  • Valid evidence for lifestyle intervention effectiveness and safety can be obtained through appropriate non-randomized research.