Infectious crystalline keratopathy: A case series

Area of Science:

• Ophthalmology
• Corneal Diseases
• Infectious Keratitis

Background:

• Infectious crystalline keratopathy (ICK) is a rare and potentially sight-threatening corneal infection.
• Penetrating keratoplasty (corneal transplant) can be a risk factor for developing ICK.
• This study focuses on ICK cases arising after corneal transplantation.

Observation:

• Three patients who underwent penetrating keratoplasty between 2010 and 2020 presented with ICK.
• Clinical examination revealed characteristic crystalline patterns indicative of ICK.
• Diagnosis was established based on clinical presentation.

Findings:

• All three patients were treated with broad-spectrum antibiotics.
• Complete resolution of the crystalline lesions was achieved in all cases with antibiotic therapy.
• The study highlights the successful management of ICK in post-keratoplasty patients.

Implications:

• Early clinical diagnosis and prompt broad-spectrum antibiotic treatment are crucial for managing ICK.
• This case series provides valuable insights into the clinical features and effective treatment of this resistant corneal infection.
• Understanding ICK management post-keratoplasty can improve patient outcomes and preserve vision.