Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

23
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
23
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

42
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
42
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

34
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
34
Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

119
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
119
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

35
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage kidney disease (ESKD). At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate...
35
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

29
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
29

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Automated ICD-10-Anchored Classification of Primary Care Text Data: Development and Evaluation of a Custom Multilabel Classifier.

JMIR medical informatics·2026
Same author

Long-term citrate treatment in high-risk kidney stone formers is not associated with metabolic adverse effects.

Clinical kidney journal·2026
Same author

Destructive Mold Osteomyelitis of the Wrist Caused by <i>Scedosporium apiospermum</i>-A Case Report.

Journal of clinical medicine·2026
Same author

Effect of Sodium Bicarbonate on Indicators of Volume Retention in Metabolic Acidosis After Kidney Transplantation: A Post-Hoc Analysis.

Kidney medicine·2026
Same author

Automated ICD-10-Anchored Classification of Primary Care Text Data: Development and Evaluation of a Custom Multilabel Classifier.

JMIR medical informatics·2026
Same author

[Polypharmacy-guideline issued by the Department of Internal Medicine (DIM) at the University Hospital Zurich (USZ)].

Praxis·2026

Related Experiment Video

Updated: Jul 18, 2025

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice
09:09

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

Published on: August 9, 2013

39.9K

Ambient temperature and kidney function in primary care patients.

Simeon Schietzel1, Stefan Zechmann2, Fabio Valeri2

  • 1Divison of Nephrology, University Hospital Bern, Bern, Switzerland.

Journal of Nephrology
|August 23, 2023
PubMed
Summary

High ambient temperatures did not consistently affect kidney function in Swiss primary care patients. A small reduction in kidney function was observed in highly vulnerable individuals, but its clinical significance remains uncertain.

Keywords:
ClimateDehydrationInjuryKidneyTemperatureWeather

More Related Videos

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.3K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.4K

Related Experiment Videos

Last Updated: Jul 18, 2025

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice
09:09

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

Published on: August 9, 2013

39.9K
Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.3K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.4K

Area of Science:

  • Environmental Health
  • Nephrology
  • Public Health

Background:

  • High ambient temperatures are linked to acute kidney injury, but evidence often comes from extreme heat events or emergency settings.
  • The impact of community-level temperature variations on kidney function in temperate climates is not well understood.

Purpose of the Study:

  • To investigate the association between ambient temperature and kidney function in a large primary care cohort in a temperate climate.
  • To assess if vulnerable patient groups experience differential effects of temperature on kidney function.

Main Methods:

  • A 9.5-year retrospective cohort study of 18,000 Swiss primary care patients (FIRE cohort).
  • Correlation of estimated glomerular filtration rate (eGFR) with daily maximum ambient temperatures across five groups ( <15°C to ≥30°C).
  • Analysis of interactions for patients with chronic heart failure, diabetes, chronic kidney disease, or on specific medications (RAAS inhibitors, diuretics, NSAIDs).

Main Results:

  • Unadjusted analyses showed higher temperatures associated with lower eGFR across all groups.
  • Adjusted models revealed no consistent association between ambient temperature and kidney function.
  • A marginal inverse association (eGFR reduction of -2.9 ml/min/1.73m²) was observed in patients with ≥3 risk factors at temperatures >25°C or >30°C compared to <15°C.

Conclusions:

  • Ambient temperature variations in a temperate climate do not show a consistent association with kidney function in the general primary care population.
  • A minor, potentially clinically irrelevant, inverse association may exist in highly vulnerable patient groups.