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Tuning Polymer Composition Leads to Activity-Stability Tradeoff in Enzyme-Polymer Conjugates

Evan A Bisirri1, Thaiesha A Wright1, Daniel K Schwartz1

  • 1Department of Chemical and Biological Engineering, University of Colorado, Boulder, Colorado 80309, United States.

Biomacromolecules
|August 23, 2023
PubMed
Summary

Modifying lipase with polymers like sulfobetaine methacrylate (SBMA) and poly(ethylene glycol) methacrylate (PEGMA) affects its stability and activity. Optimizing the polymer ratio enhances enzyme productivity for industrial applications.

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