Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Calcitonin Gene-related Peptide Inhibitors May Reduce Odds of Gabapentinoid Use in Patients with Spinal Cord Injury/Disorder.

American journal of physical medicine & rehabilitation·2026

Same author

Glucagon-Like Peptide-1 Receptor Agonists: Are We Swapping One Public Health Crisis for Another?

Australasian journal on ageing·2026

Same author

Functional Outcomes After Decompressive Craniectomy.

Neurosurgery clinics of North America·2026

Same author

2025 ESC/EACTS valvular heart disease guidelines: key updates and surgical implications for cardiac surgeons.

Current opinion in cardiology·2026

Same author

Schwannoma causing chronic medial calf pain in a recreational skiing and running athlete: a case report.

The Journal of the Canadian Chiropractic Association·2026

Same author

Point cloud dosimetry framework for preclinical microbeam radiation therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2025

Search research articles

Related Experiment Video

Updated: Jul 18, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

Porocarcinoma Development in a Prior Trauma Site

Christopher White¹, Michael McBride¹, Emily Rubenstein¹

¹Dr. White is from Dermatology Partners, Strongsville, Ohio. Dr. McBride is from the Department of Dermatology, HonorHealth Medical Group, Phoenix, Arizona. Dr. Rubenstein is from the Swedish Skin Institute, Chicago, Illinois.

|August 23, 2023

Summary

No abstract available in PubMed .

More Related Videos

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

Porcine As a Training Module for Head and Neck Microvascular Reconstruction

Porcine As a Training Module for Head and Neck Microvascular Reconstruction

Published on: September 29, 2018

Related Experiment Videos

Last Updated: Jul 18, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

Porcine As a Training Module for Head and Neck Microvascular Reconstruction

Porcine As a Training Module for Head and Neck Microvascular Reconstruction

Published on: September 29, 2018