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Updated: Jul 18, 2025

Hemogenic Endothelium Differentiation from Human Pluripotent Stem Cells in A Feeder- and Xeno-free Defined Condition
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Engineered hematopoietic and immune cells derived from human pluripotent stem cells

Yun Chang1, Sydney N Hummel1, Juhyung Jung1

  • 1Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana; Purdue University Institute for Cancer Research, West Lafayette, Indiana.

Experimental Hematology
|August 23, 2023
PubMed
Summary

Human pluripotent stem cells (hPSCs) offer a scalable and cost-effective alternative to human hematopoietic stem cells (HSCs) for cell therapies. Engineering hPSCs advances hematopoietic stem and progenitor cell (HSPC) differentiation for improved cancer immunotherapy and blood disease treatments.

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