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Emergence of Monkeypox (MPX): A Close Relative of Small Pox During COVID-19 Era

Ivneet Kour1, Lipika Singhal1, Sonia Mehta2

  • 1Department of Microbiology, Government Medical College & Hospital, Chandigarh, 160030, India.

Infectious Disorders Drug Targets
|August 24, 2023
PubMed

Insights

Monkeypox (MPX), a zoonotic disease, has re-emerged globally, posing a significant public health threat. Factors like the cessation of smallpox vaccinations may contribute to its spread and evolving clinical manifestations.

Area of Science:

  • * Public Health
  • * Infectious Diseases
  • * Epidemiology

Background:

  • * Emerging zoonotic diseases, like Monkeypox (MPX), pose significant global health security risks.
  • * MPX, first identified in the Democratic Republic of the Congo, has spread beyond Central Africa.
  • * The recent global outbreak has led to its declaration as a public health emergency of international concern.

Purpose of the Study:

  • * To discuss the recent history and epidemiology of Monkeypox outbreaks.
  • * To analyze the evolving clinical manifestations of the disease.
  • * To explore potential causes for the increase in MPX cases, including the impact of smallpox vaccination cessation.

Main Methods:

  • * Review of recent MPX outbreak data and historical records.
  • * Analysis of epidemiological trends and geographical spread.
  • * Examination of clinical case reports and potential contributing factors.

Main Results:

  • * As of August 2022, over 40,000 MPX infections were confirmed in 68 countries, predominantly in Europe and Southeast Asia.
  • * MPX has demonstrated an expanding geographical reach and evolving clinical presentations.
  • * The cessation of smallpox (SPX) vaccinations is considered a potential factor in the increased susceptibility and spread.

Conclusions:

  • * The re-emergence of Monkeypox represents a substantial global health challenge.
  • * Understanding the changing epidemiology and clinical features is crucial for effective control.
  • * Further research into the role of vaccination history and other contributing factors is warranted.
Keywords:
COVID-19Eradication of small poxMPX and SPXdemocratic republic of the congo (DRC).emerging zoonotic diseasevaccines

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