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The relationship between shift work pattern and thyroid stimulating hormone in female workers.

Hun Jeong¹, Chang Ho Chae¹, Jun Ho Lee¹

¹Department of Occupational and Environmental Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Annals of Occupational and Environmental Medicine

|August 24, 2023

Summary

Shift work increases the risk of subclinical hypothyroidism. Irregular three-shift work poses the highest risk compared to non-shift work, highlighting the importance of considering shift type in thyroid health evaluations.

Keywords:

Shift work type Subclinical hypothyroidism Thyroid-stimulating hormone

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Area of Science:

Endocrinology
Occupational Health
Chronobiology

Background:

Shift work disrupts circadian rhythms, impacting physical and mental health.
Previous studies suggest a link between shift work and thyroid stimulating hormone (TSH).
Limited research exists on TSH level variations across different shift work schedules.

Purpose of the Study:

To investigate the relationship between shift work type and TSH levels.
To assess the risk of subclinical hypothyroidism in different shift work patterns.

Main Methods:

1,318 female workers' medical data (2015-2019) were analyzed.
Shift work categorized as non-shift, regular 2 shifts, or irregular 3 shifts.
Generalized Estimation Equation (GEE) used to compare subclinical hypothyroidism risk over 5 years.

Main Results:

Shift work was associated with a higher risk of subclinical hypothyroidism.
Irregular three-shift workers showed a significantly higher risk (OR=2.02) compared to non-shift workers.
Two-shift workers also had an increased risk (OR=1.81) versus non-shift workers.

Conclusions:

Shift work type is a significant factor in subclinical hypothyroidism risk.
Findings suggest incorporating shift work details into thyroid function assessments.
Further research may inform targeted interventions for shift workers' thyroid health.