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Food-Grade Physically Unclonable Functions.

Abidin Esidir1,2, Nilgun Kayaci1, N Burak Kiremitler1,2

  • 1ERNAM─Nanotechnology Research and Application Center, Erciyes University, Kayseri 38039, Turkey.

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Summary
This summary is machine-generated.

Researchers developed edible security labels using food-grade corn starch and erythrosine B. These labels offer a low-cost, sustainable solution to combat counterfeit drugs and food products.

Keywords:
corn starchedibleencodingfluorescencephysically unclonable function (PUF)

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Area of Science:

  • Materials Science
  • Food Science
  • Biotechnology

Background:

  • Counterfeit pharmaceuticals and food pose significant global health risks.
  • Current anti-counterfeiting measures often lack integration with product safety and sustainability.
  • Edible security labels are needed for direct application on food and drugs.

Purpose of the Study:

  • To fabricate novel, edible security labels using food-grade materials.
  • To develop a physically unclonable function (PUF) based on microparticle characteristics.
  • To assess the performance and biocompatibility of the developed security labels.

Main Methods:

  • Fabrication of fluorescent corn starch (CS) and erythrosine B (ErB) microparticles (CS@ErB).
  • Spin-coating of CS@ErB particles onto an edible gelatin film for random positioning.
  • Construction of PUF keys using optical and fluorescence microscopy of particle arrangements.
  • Biocompatibility assessment using murine fibroblast cell assays.

Main Results:

  • Successfully fabricated edible security labels from food-grade corn starch and erythrosine B.
  • Developed a PUF-based security system leveraging the unique random arrangement of CS@ErB microparticles.
  • Demonstrated high performance of PUFs through uniformity, uniqueness, and randomness analysis.
  • Confirmed the biocompatibility of the fabricated security labels.

Conclusions:

  • The developed edible security labels offer a promising, low-cost, and sustainable anti-counterfeiting solution.
  • This approach utilizes readily available food-grade materials for enhanced product security.
  • The PUF-based system provides a robust method for verifying product authenticity.