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[Clinical experience with cefixime in the pediatric field]
The Japanese Journal of Antibiotics
|April 1, 1986
Summary
Cefixime (CFIX) effectively treated pediatric bacterial infections in 25 children, showing good clinical response in most cases. This antibiotic demonstrated a favorable safety profile and palatability, suggesting its utility in pediatric care.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Pharmacology
- Bacteriology
Context:
- Acute bacterial infections are common in children.
- Cefixime is a third-generation cephalosporin antibiotic.
- Evaluating new antibiotic treatments for pediatric populations is crucial.
Purpose:
- To assess the clinical efficacy and safety of oral Cefixime in children with acute bacterial infections.
- To evaluate the bacteriological response to Cefixime treatment.
- To determine the tolerability and acceptance of Cefixime by pediatric patients.
Summary:
- Twenty-five children with infections like tonsillitis, bronchitis, bronchopneumonia, and UTI received oral Cefixime.
- Excellent clinical response was observed in 23 children.
- Bacteriological success was noted in 14 of 16 patients; side effects were minimal (soft stool, eosinophilia in one child each).
Impact:
- Cefixime demonstrates significant clinical effectiveness and a good safety profile for treating various pediatric bacterial infections.
- The antibiotic's palatability suggests good patient compliance in children.
- Findings support Cefixime as a valuable therapeutic option for pediatric bacterial infections.