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Updated: Jul 18, 2025

Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
Watchful Eye Prevents Catastrophe in Case of Malignant Hyperthermia: A Case Report
Joseph Brenner1, Emily Cage2, Kyle Andrews3
1University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Case:
A 49-year-old woman presented with a displaced left posterior wall acetabular fracture-dislocation and a left comminuted intra-articular distal radius fracture sustained in a motor vehicle accident. Fifteen minutes after anesthesia induction for operative fixation of the fractures, the patient experienced severe hypertension, increased end-tidal carbon dioxide, and fever. A diagnosis of malignant hyperthermia (MH) was made before incision. The patient was medically stabilized, and her acetabular fracture-dislocation was placed in skeletal traction until she was deemed fit for surgery 4 days later.
Conclusion:
This case report highlights the importance of early recognition of MH and perioperative management.
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