[Double-blind study with cyclosporin A eyedrops in healthy probands]

Cyclosporin-A eye drops initiate an immunosuppression after corneal transplantation in rabbits as well as in humans, as experimental and clinical studies showed. A tolerance study with 12 volunteers (healthy and without any ophthalmological disease) was designed as a randomized double-blind study. Apart from two objectively slight intolerance reactions there were no side-effects. The use of these drops after corneal transplantation is discussed.