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Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma
Ikemsinachi C Nzenwa1, Margaret Berquist1, Toby J Brenner1
1Saint Joseph Regional Medical Center, Mishawaka, Indiana, USA.
Case Reports in Critical Care
|August 25, 2023
Summary
Type B lactic acidosis, often linked to cancer, requires prompt treatment of both the acidosis and the underlying malignancy. Early diagnosis and combined therapies improve patient outcomes, as seen in this mantle cell lymphoma case.
Area of Science:
- Oncology
- Internal Medicine
- Biochemistry
Background:
- Type B lactic acidosis is a rare, life-threatening condition where acid production exceeds the liver's ability to clear it.
- It occurs without organ hypoperfusion and is frequently associated with hematologic and solid tumors, linked to the Warburg effect in cancer cells.
- Prognosis is poor without addressing the underlying malignancy.

