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Published on: July 16, 2020
Community-Acquired Pseudomonas aeruginosa Meningitis in a Pediatric Patient
Alexander Cotran-Lenrow1, Lidia S Tefera2, Matthew Douglas-Vail3
1Department of Microbiology, Partners in Health, Harper, LBR.
Abstract:
This case report presents a rare and significant case of community-acquired Pseudomonas aeruginosa meningitis in a healthy 13-month-old male patient in rural Liberia. Pseudomonas aeruginosa meningitis, particularly in the absence of predisposing factors, is a rare occurrence with a high mortality rate. The challenges in diagnosing this condition, especially in resource-limited settings, are highlighted. The patient initially presented with fever, seizures, and altered consciousness, and lumbar puncture revealed turbid cerebrospinal fluid (CSF) with elevated white blood cell count. Subsequent CSF culture confirmed Pseudomonas aeruginosa infection. Prompt initiation of appropriate antibiotic therapy, including a push dose of meropenem, resulted in clinical improvement. However, the patient exhibited post-meningitis sequelae, including hearing and visual impairments. Comprehensive follow-up care and rehabilitation services are crucial for managing these long-term complications. By sharing this case, we aim to increase awareness and facilitate early recognition of Pseudomonas aeruginosa meningitis, leading to improved patient care and outcomes in similar clinical scenarios.
Insights
This case report details a rare community-acquired Pseudomonas aeruginosa meningitis in a Liberian infant. Early diagnosis and treatment are vital, though long-term complications like hearing loss can occur.
Area of Science:
- Pediatric Infectious Diseases
- Neuroscience
- Microbiology
Background:
- Community-acquired bacterial meningitis poses significant risks, especially in resource-limited settings.
- Pseudomonas aeruginosa meningitis is exceptionally rare in healthy children, often associated with severe outcomes.
Observation:
- A 13-month-old boy in rural Liberia presented with fever, seizures, and altered consciousness.
- Cerebrospinal fluid analysis revealed turbid fluid with elevated white blood cells, confirming bacterial meningitis.
- Cerebrospinal fluid culture identified Pseudomonas aeruginosa as the causative pathogen.
Findings:
- Prompt administration of antibiotics, including meropenem, led to clinical improvement.
- The patient developed significant post-meningitis sequelae, including hearing and visual impairments.
- This case highlights the challenges of diagnosing rare infections in resource-limited environments.
Implications:
- Increased awareness and early recognition of Pseudomonas aeruginosa meningitis are crucial for timely intervention.
- Effective management requires prompt antibiotic therapy and comprehensive follow-up care.
- Addressing long-term sequelae through rehabilitation services is essential for improving patient outcomes.
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