Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

10.9K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.9K
Blood Transfusion01:15

Blood Transfusion

613
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
613
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

29
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
29
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

360
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
360

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2025
Same author

Consistent supply of global plasma for global patients.

Vox sanguinis·2024
Same author

Live imaging of the airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread.

Research square·2023
Same author

Effects of donation frequency on U.S. source plasma donor health.

Transfusion·2023
Same author

Prospective, open-label, multicenter clinical study to assess the performance of a new donation system for the collection of source plasma.

Journal of clinical apheresis·2023
Same author

AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5.

The EMBO journal·2022
Same journal

Investigation of the preanalytical stability of blood donor samples.

Transfusion·2026
Same journal

The need for dried plasma-Still a national issue: Where are we and recommendations.

Transfusion·2026
Same journal

Spray dried plasma manufactured from apheresis and whole blood derived plasma.

Transfusion·2026
Same journal

Identification of a novel ABO*A1.01 allele with c.562C>T (p.Arg188Cys) mutation associated with A<sub>el</sub> phenotype in a Chinese individual.

Transfusion·2026
Same journal

AABB survey on directed blood donation practices.

Transfusion·2026
Same journal

Cost analysis considerations for red blood cell matching to mitigate alloimmunization in patients with sickle cell disease.

Transfusion·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
06:40

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

166

Why do US source plasma donors stop donating?

Michelle Fransen1, Mark Becker2, Janet Hershman3

  • 1Plasma Protein Therapeutics Association, Annapolis, Maryland, USA.

Transfusion
|August 25, 2023
PubMed
Summary
This summary is machine-generated.

Most source plasma (SP) donors stop donating due to convenience, not health concerns. Understanding these reasons helps maintain a healthy donor pool for vital plasma-derived medicines.

Keywords:
donor lapseplasma donorplasmavigilancesource plasma

More Related Videos

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.2K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

19.5K

Related Experiment Videos

Last Updated: Jul 18, 2025

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
06:40

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

166
A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.2K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

19.5K

Area of Science:

  • Plasma Donation Research
  • Donor Health & Well-being
  • Public Health

Background:

  • Source plasma (SP) donation is crucial for producing life-saving plasma-derived medicinal products.
  • Maintaining the health of frequent SP donors is essential given the global demand.
  • Understanding donor motivations for donation lapses is key to retention.

Purpose of the Study:

  • To explore the self-reported reasons why frequent source plasma donors in the US stop donating.
  • To identify the primary factors contributing to donation lapses among SP donors.

Main Methods:

  • A longitudinal cohort study involved 5608 SP donors from 14 centers.
  • Donors were grouped by donation frequency over 12 months.
  • A survey was administered to 1448 donors who lapsed for 6+ months.

Main Results:

  • 37.6% of surveyed lapsed donors (545) returned surveys; 63% were female.
  • Convenience (e.g., schedule conflicts) was the primary reason for stopping (69.1%).
  • Health concerns, possibly or uncertainly related to plasmapheresis, accounted for 45.5% of responses.

Conclusions:

  • Convenience is the leading self-reported reason for SP donor lapses in the US.
  • While less frequent, health concerns are also cited by donors across all donation frequencies.
  • Findings suggest most donor lapses are not directly linked to perceived negative health impacts from plasmapheresis.