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Published on: November 26, 2013
Life-Threatening Subglottic Thrombus Formation after Administration of Nebulized Tranexamic Acid
Andrew Awadallah1, Michael Armstrong2, Aisha Aden1
1Alix School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
We present a case of subglottic thrombus formation after administration of nebulized tranexamic acid (TXA) for postoperative hemoptysis following CO2 laser wedge excision of subglottic stenosis. Although other factors certainly could have resulted in postoperative bleeding and subsequent thrombus formation, the patient's rapid decompensation following administration of nebulized TXA suggests a direct effect. We recommend implementing an airway action plan regarding TXA use for patients presenting to the emergency department with postoperative hemorrhage following otolaryngology procedures. Laryngoscope, 134:1356-1358, 2024.
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