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Streptococcus intermedius Brain Abscess with Lung Abscess and Aortic Valve Endocarditis: A Case Report and Literature
Francesca Gavaruzzi1, Pierangelo Chinello1, Giuseppe Cucinotta1
1National Institute for Infectious Diseases "L. Spallanzani", 00149 Rome, Italy.
Abstract:
Streptococcus intermedius is frequently associated with brain and liver abscesses, while pleuropulmonary infections are considered rarer. Even less frequent is the association of lung and brain abscesses due to this agent with infective endocarditis. We describe the case of a 40-year-old man complaining of cough, fever, and headache who was diagnosed with a brain abscess due to S. intermedius, a concomitant lung abscess, and aortic native valve endocarditis. He was treated with surgical drainage of the brain abscess and a 4-week course of intravenous ceftriaxone, followed by oral amoxicillin/clavulanate, obtaining healing of the lesions without relapse of the infection.
Insights
Streptococcus intermedius rarely causes lung and brain abscesses simultaneously. This case highlights a rare instance of these infections alongside infective endocarditis, successfully treated with antibiotics and surgery.
Area of Science:
- Infectious Diseases
- Neurology
- Cardiology
Background:
- Streptococcus intermedius commonly causes abscesses in the brain and liver.
- Pleuropulmonary infections are less common, and concurrent lung and brain abscesses are rare.
Observation:
- A 40-year-old male presented with cough, fever, and headache.
- Diagnosis revealed a brain abscess caused by S. intermedius, a concurrent lung abscess, and native aortic valve endocarditis.
Findings:
- Successful treatment involved surgical drainage of the brain abscess.
- A 4-week course of intravenous ceftriaxone followed by oral amoxicillin/clavulanate achieved lesion healing.
Implications:
- This case underscores the importance of considering S. intermedius in complex abscess presentations.
- Highlights the successful management of a rare triad of S. intermedius infections.
- Emphasizes the need for prompt diagnosis and multimodal treatment for such severe infections.
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