Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

483
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
483
Supercritical Fluid Chromatography01:18

Supercritical Fluid Chromatography

279
Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
279
Size-Exclusion Chromatography01:08

Size-Exclusion Chromatography

643
In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
643
Optimizing Chromatographic Separations01:15

Optimizing Chromatographic Separations

433
Optimizing chromatographic separations is crucial for obtaining clean separations in a minimum amount of time. Optimization is required for several factors, including kinetic effects related to band broadening, plate height, capacity factor, and separation factor.
Band broadening refers to spreading solute bands as they travel through the column. This broadening can impact resolution. Plate height (H) represents the length required for one theoretical plate. A lower plate height corresponds to...
433
Ion Exchange01:17

Ion Exchange

621
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
621
Affinity Chromatography01:03

Affinity Chromatography

731
Affinity chromatography is a powerful technique extensively utilized for separating and purifying specific biomolecules from complex mixtures. It capitalizes on the highly selective binding between an analyte and its counterpart, such as antibody-antigen interactions. The counterpart is immobilized on the stationary phase, forming an affinity column. The stationary phase typically consists of solid support, such as agarose or porous glass beads, immobilizing the affinity ligand. The mobile...
731

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Hydrocarbon Organic Cage-Based Porous Liquid for Ethylene/Ethane Separation.

Journal of the American Chemical Society·2026
Same author

Lipopolysaccharide hydrolysis-targeting nano-chimeras detoxify endotoxin through specific adsorption and efficient degradation.

Nature communications·2026
Same author

Adaptive Cavity-Enabled Crystalline Chirality in Nanocarbon Cages.

Angewandte Chemie (International ed. in English)·2026
Same author

Cyanine-modified ssODNs enhance CRISPR-Cas9 HDR in stem cell embryo models via chromatin and chemical modulation.

Nature communications·2026
Same author

Synthesis and guest inclusion for molecular catcher-based structure determination.

Nature protocols·2026
Same author

Facile Preparation of a Poly[2]Catenane Network Using Self-Assembled [2]Catenane Unit.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jul 18, 2025

Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.8K

Industrial Separation Challenges: How Does Supramolecular Chemistry Help?

Gengwu Zhang1, Weibin Lin1, Feihe Huang2,3

  • 1Smart Hybrid Materials Laboratory (SHMs), Chemistry Program, Advanced Membranes and Porous Materials Center, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.

Journal of the American Chemical Society
|August 25, 2023
PubMed
Summary

Porous organic cages and macrocycles offer sustainable alternatives to energy-intensive distillation for hydrocarbon separations. These advanced materials selectively adsorb molecules, paving the way for greener chemical industry practices.

More Related Videos

Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

9.0K
Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials
09:05

Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials

Published on: May 15, 2015

14.8K

Related Experiment Videos

Last Updated: Jul 18, 2025

Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.8K
Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

9.0K
Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials
09:05

Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials

Published on: May 15, 2015

14.8K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Sustainable Chemistry

Background:

  • The chemical industry faces increasing pressure for sustainable and environmentally friendly practices.
  • Traditional separation methods like distillation are energy-intensive, necessitating more efficient alternatives.
  • New materials are crucial for developing advanced separation technologies.

Purpose of the Study:

  • To review recent advances in porous organic cages and macrocycles for selective molecular adsorption.
  • To highlight host-guest interactions enabling selective hydrocarbon separations.
  • To discuss the potential of these materials for industrial applications.

Main Methods:

  • Focus on porous organic cages and macrocycles as adsorbent materials.
  • Analysis of host-guest interactions driving selective adsorption.
  • Review of recent literature on receptor-based adsorbent materials for hydrocarbon separations.

Main Results:

  • Porous organic cages and macrocycles demonstrate selective adsorption of guest molecules.
  • These materials exhibit molecular sieving behavior.
  • Receptor-based adsorbents with voids or functional groups can selectively capture target molecules.

Conclusions:

  • Receptor-based adsorbent materials show promise for sustainable hydrocarbon separations.
  • Understanding molecular-level interactions is key to designing tailored molecular sieves.
  • Further development could transition adsorbent material-based separations from lab to industry.