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Recent developments in electromigration techniques related to pharmaceutical and biomedical analysis - A review
Chiara Fanali1, Susanna Della Posta1, Alessandra Gentili2
1Department of Science and Technology for Humans and the Environment, University Campus Bio-Medico of Rome, Rome, Italy.
Capillary electrophoresis (CE) offers efficient and cost-effective analysis of pharmaceutical compounds, crucial for combating counterfeit drugs. This review highlights CE
Area of Science:
- Analytical Chemistry
- Pharmaceutical Analysis
Background:
- The proliferation of counterfeit drugs necessitates advanced analytical methods for pharmaceutical compound analysis.
- Modern analytical techniques are vital for drug production, quality control, and pharmacokinetic studies.
Purpose of the Study:
- To review the features and limitations of capillary electromigration techniques, particularly capillary electrophoresis (CE).
- To present recent applications of CE in pharmaceutical compound analysis from 2021-2023.
Main Methods:
- Review of scientific literature focusing on capillary electromigration techniques.
- Discussion of capillary electrophoresis (CE) principles, advantages, and limitations.
- Compilation of selected CE applications in pharmaceutical analysis.
Main Results:
- Capillary electrophoresis (CE) demonstrates high efficiency and cost-effectiveness for pharmaceutical analysis.
- CE offers advantages such as reduced solvent consumption and versatile separation mechanisms.
- Recent studies showcase CE's utility in analyzing diverse pharmaceutical compounds.
Conclusions:
- Capillary electrophoresis is a powerful and advantageous technique for pharmaceutical analysis.
- CE plays a significant role in ensuring drug quality and safety.
- Ongoing research continues to expand the applications of CE in pharmaceutical science.
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