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CD30 in Cutaneous Pathology
Angel Fernandez-Flores1,2,3, David Cassarino4
1Dermatopathologist, Department of Histopathology, University Hospital El Bierzo, Ponferrada, Spain.
Abstract:
The discovery of CD30 as a diagnostic marker was essential in the identification of not only some lymphomas but also many other solid tumors and benign reactive conditions. Many CD30+ cutaneous disorders and tumors have been categorized since the identification of the marker. With the design of targeted therapies against CD30+ tumoral cells, the interest in CD30 determination was not only diagnostic but also mainly therapeutic. In this article, we explore the historical aspects of the discovery of CD30 and examine the main CD30-related cutaneous pathology, susceptible of anti-CD30 modern treatments.
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