Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

251
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
251
Skin Cancer01:30

Skin Cancer

4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Metastasis02:30

Metastasis

5.6K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dangerous liaisons: the peri-transplant respiratory microbiota and their impact on lung transplantation outcomes.

Journal of thoracic disease·2026
Same author

Volumetric Analysis of Ridge Preservation Using Bio-Oss<sup>®</sup> Collagen: A Retrospective Cohort Study Based on CBCT and Panoramic Radiographs.

Medicina (Kaunas, Lithuania)·2026
Same author

TMJ Replacement as a System: Results of an International Surgeon Survey on Design, Fixation, Materials, and Digital Workflow.

Craniomaxillofacial trauma & reconstruction·2026
Same author

A Cross-Species Enhancer-AAV Toolkit for Cell Type-Specific Targeting Across the Basal Ganglia.

bioRxiv : the preprint server for biology·2026
Same author

Nasal Fracture During Maxillary Expansion-A Rare Complication?

Reports (MDPI)·2026
Same author

Comparing Heparin and Heparin Mimetics in Targeting Immunomodulatory Proteins from Platelets to Activate T Cell-Dependent Immune Response in Oncology.

ACS pharmacology & translational science·2026

Related Experiment Video

Updated: Jul 18, 2025

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
05:42

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

1.1K

Metastases of OSCC Based on Oral Lichen Ruber Planus.

Katharina Theresa Obermeier1, Sabina Noreen Wuersching2, Paris Liokatis1

  • 1Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, Ludwig Maximilian University Munich, 80337 Munich, Germany.

Cancers
|August 26, 2023
PubMed
Summary

Oral lichen ruber planus (OLP) can transform into oral squamous cell carcinoma (OSCC) with a lower metastasis risk but a higher risk for secondary tumors. Careful follow-up is crucial for these patients.

Keywords:
OSCClymph nodal spreadingmetastasesneck dissectionoral lichen rubersecond metachronous tumor

More Related Videos

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
12:03

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma

Published on: July 25, 2011

19.4K
Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

11.5K

Related Experiment Videos

Last Updated: Jul 18, 2025

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
05:42

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

1.1K
Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
12:03

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma

Published on: July 25, 2011

19.4K
Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

11.5K

Area of Science:

  • Oral Medicine
  • Oncology
  • Pathology

Background:

  • Oral lichen ruber planus (OLP) is a chronic inflammatory oral mucosa disease.
  • Malignant transformation to oral squamous cell carcinoma (OSCC) occurs in 1-2% of OLP cases.
  • Treatment for OLP-associated OSCC is debated due to tumor characteristics.

Purpose of the Study:

  • To compare metastasis development and survival in OLP patients with OSCC versus OSCC patients without OLP.
  • To analyze the characteristics of OSCC arising in the context of OLP.

Main Methods:

  • Retrospective overview of 103 patients treated for OLP.
  • Comparison of metastasis rates and survival between OLP-associated OSCC and non-OLP OSCC groups.

Main Results:

  • OSCC in OLP patients showed a significantly lower risk of lymph node spreading (p=0.013).
  • Patients with OSCC without OLP had a 4.76-fold higher risk for lymph node spreading.
  • Second metachronous tumors were more frequent in patients with OLP-associated OSCC.

Conclusions:

  • OSCC based on OLP is more common in females, is highly differentiated, has lower metastasis risk, but a higher risk for second tumors.
  • Special attention and cautious adjuvant therapy planning are needed for OLP-associated OSCC.
  • Close clinical follow-up is essential due to the risk of recurrence or new primary tumors.