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Related Concept Videos

Overview of Cell Signaling01:23

Overview of Cell Signaling

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Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
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What is Cell Signaling?02:03

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Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
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Diversity in Cell Signaling Responses01:22

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The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
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Types of Signaling Molecules01:32

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In multicellular organisms, many molecules transmit signals between cells to pass information. These signals vary in complexity and include small peptides, nucleotides, steroids, fatty acid derivatives, and dissolved gases such as nitric oxide. Some signaling molecules diffuse through the plasma membrane to act locally between neighboring cells or travel long distances. Others remain attached to the cell surface, transmitting information to other cells only when they make contact. In some...
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Chemical Signaling in the Endocrine System01:08

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A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
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Endocrine Signaling01:45

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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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Accessing the Cytotoxicity and Cell Response to Biomaterials
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Cellular Signaling for Dental Physiological Functions.

Takehito Ouchi1,2, Taneaki Nakagawa2

  • 1Department of Physiology, Tokyo Dental College, Tokyo 101-0061, Japan.

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|August 26, 2023
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Summary

Teeth are vital tissues for chewing, speaking, and aesthetics. Understanding their complex structure is key to improving dental health and treatments.

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Area of Science:

  • Dentistry and Regenerative Medicine
  • Biomaterials Science

Background:

  • Teeth are complex, multifunctional biological tissues crucial for mastication, phonetics, and facial aesthetics.
  • The intricate structure of teeth, including enamel, dentin, and pulp, supports these vital functions.

Discussion:

  • The multifaceted nature of dental tissues necessitates a comprehensive understanding for effective therapeutic interventions.
  • Current research explores advanced biomaterials and regenerative approaches to address dental tissue defects and diseases.

Key Insights:

  • Teeth serve critical roles beyond basic functions, impacting overall health and quality of life.
  • The unique composition and properties of dental tissues present significant challenges and opportunities in restorative dentistry.

Outlook:

  • Future research aims to enhance dental tissue regeneration and develop novel biomimetic materials.
  • Improving our knowledge of tooth development and maintenance will drive innovations in preventing and treating dental conditions.