Immune complexes in the serum of hamsters with transplanted melanomas

Rosette EA and EAC inhibition test was used to compare levels of immune complexes in the serum of control hamsters and of hamsters with transplanted melanomas of the same origin, but differing in malignancy. The serum of individual animals with transplanted melanomas was found to cause a higher rosette inhibition. Inhibitory rate was more marked in hamsters with amelanotic tumors which grew faster and caused the death of an animal within a shorter time.