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A Comparison of Slow Infusion Intermittent Feeding versus Gravity Feeding in Preterm Infants: A Randomized Controlled

Funda Yavanoglu Atay1, Ozlem Bozkurt2, Suzan Sahin3

  • 1Department of Pediatrics, Division of Neonatology, Umraniye Training and Research Hospital, 34764 Istanbul, Türkiye.

Children (Basel, Switzerland)
|August 26, 2023
PubMed

Insights

Slow infusion feeding (SIF) may be a better option for preterm infants at risk of feeding intolerance. This method reduced gastric residuals and non-per-oral status compared to intermittent bolus feeding (IBF).

Area of Science:

  • Neonatology
  • Pediatric Gastroenterology
  • Infant Nutrition

Background:

  • Ensuring adequate growth in preterm infants relies on the timely transition to full enteral feeding.
  • Feeding intolerance is a common complication in preterm infants, potentially hindering nutritional support and growth.

Purpose of the Study:

  • To compare the efficacy of slow infusion feeding (SIF) versus intermittent bolus feeding (IBF) in facilitating the transition to full enteral feeding in preterm infants.
  • To evaluate the impact of these feeding methods on feeding intolerance and related outcomes.

Main Methods:

  • A prospective, randomized controlled study involving preterm infants (gestational age 24 + 0/7 to 31 + 6/7 weeks).
  • Infants were randomized to either SIF (infusion pump over 1 hour every 3 hours) or IBF (gravity-based via syringe, 10-30 min).
  • Primary outcomes included time to full enteral feeding and incidence of feeding intolerance.

Main Results:

  • No significant difference in the time to achieve full enteral feeding between SIF and IBF groups (p = 0.20).
  • The SIF group demonstrated significantly fewer instances of gastric residual volume exceeding 50% (p = 0.01).
  • Infants in the SIF group experienced a significantly shorter duration of non-per-oral (NPO) status (p = 0.03).

Conclusions:

  • Slow infusion feeding (SIF) is a suitable alternative for preterm infants experiencing or at high risk of feeding intolerance.
  • SIF may offer advantages in managing gastric residuals and reducing periods of nil by mouth.
  • This feeding strategy supports nutritional goals in vulnerable preterm populations.
Abstract

Keywords:
feeding intolerancefeeding methodsfull enteral feedingpreterm

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