Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

4.3K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.3K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

154
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
154
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

114
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
114

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility study of image reconstruction for a forceps-type positron emission counter: a simulation-based algorithm comparison.

Physics in medicine and biology·2026
Same author

Sub-0.5-mm Resolution PET Versus Autoradiography: Comparison of mGluR1 Concentrations in Mouse Brain.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Ultra-dense lutetium oxide ceramic scintillators for positron emission tomography.

Physics in medicine and biology·2026
Same author

Selection of Radiological Physics and Technology Awards 2025.

Radiological physics and technology·2026
Same author

Erratum: Optical imaging for the characterization of radioactive carbon and oxygen ion beams (2019<i>Phys. Med. Biol</i>.<b>64</b>115009).

Physics in medicine and biology·2026
Same author

Registration accuracy of amyloid/tau-PET to brain MRI using modified SPM method.

Annals of nuclear medicine·2026

Related Experiment Video

Updated: Jul 18, 2025

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

6.9K

Current and Future PET Imaging for Multiple Myeloma.

Mariko Ishibashi1, Miwako Takahashi2, Taiga Yamaya2

  • 1Department of Microbiology and Immunology, Nippon Medical School, Tokyo 113-8602, Japan.

Life (Basel, Switzerland)
|August 26, 2023
PubMed
Summary

Positron emission tomography (PET) offers insights into multiple myeloma (MM) staging. Novel PET radiotracers show promise for improved MM detection and future therapeutic strategies.

Keywords:
PETimmuno-Pminimal residual diseasemultiple myelomaradiotracertumor microenvironment

More Related Videos

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
07:45

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

415
Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography
09:41

Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography

Published on: January 20, 2023

1.9K

Related Experiment Videos

Last Updated: Jul 18, 2025

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

6.9K
Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
07:45

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

415
Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography
09:41

Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography

Published on: January 20, 2023

1.9K

Area of Science:

  • Nuclear medicine
  • Oncology
  • Medical imaging

Background:

  • Positron emission tomography (PET) is crucial for noninvasive tumor staging and therapy response assessment.
  • 18F-FDG PET is commonly used for multiple myeloma (MM) lesion assessment but has limitations in sensitivity compared to newer methods.
  • Emerging PET technologies aim to overcome current limitations in MM imaging.

Purpose of the Study:

  • To review recent advancements in PET imaging for multiple myeloma (MM) detection.
  • To explore the potential of novel PET radiotracers beyond 18F-FDG for MM.
  • To discuss the future implications of PET technologies in MM therapeutic strategies.

Main Methods:

  • Review of recent studies on 18F-FDG PET in MM.
  • Analysis of preclinical and clinical research on novel PET radiotracers (64Cu-LLP2A, 68Ga-pentixafor, 89Zr-daratumumab) for MM.
  • Exploration of PET imaging for tumor-infiltrating lymphocytes in cancer, with a note on its absence in MM.

Main Results:

  • 18F-FDG PET is established for MM lesion assessment but is less sensitive than flow cytometry and sequencing.
  • Novel PET radiotracers targeting MM cell surface antigens have been developed.
  • Research into PET imaging of tumor-infiltrating lymphocytes is ongoing in cancer but not yet applied to MM.

Conclusions:

  • Novel PET radiotracers offer improved sensitivity and specificity for MM detection.
  • Future PET technologies hold significant potential for developing advanced therapeutic strategies for MM.
  • Further research is needed to integrate novel PET imaging into MM management and to explore prognostic markers like tumor-infiltrating lymphocytes.