Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.1K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.1K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

858
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
858

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AIF, CK5/6, and CK20 in Bladder Urothelial Carcinoma: A Cross-Sectional Immunohistochemical Study of Grade and Stage Associations.

Journal of clinical medicine·2026
Same author

Glycosylation of Extracellular Vesicles: Analytical and Translational Insights into Biomarker Discovery and Regenerative Medicine.

International journal of molecular sciences·2026
Same author

Exploratory Analysis of Candidate Gene Variants in Developmental Dysplasia of the Hip: Evidence for the Role of GDF5 rs143384.

Genes·2026
Same author

Current Applications and Future Perspectives of Artificial Intelligence in Face-Driven Orthodontics: A Scoping Review.

Biomimetics (Basel, Switzerland)·2026
Same author

Comment on Hasan et al. Clinico-Pathological Features and Immunohistochemical Comparison of p16, p53, and Ki-67 Expression in Muscle-Invasive and Non-Muscle-Invasive Conventional Urothelial Bladder Carcinoma. <i>Clin. Pract.</i> 2023, <i>13</i>, 806-819.

Clinics and practice·2026
Same author

Optimizing Ki-67 and E-Cadherin Thresholds for Improved Grade and Stage Classification in Urothelial Bladder Cancer.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jul 18, 2025

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.3K

Tissue Engineering and Stem Cell Therapy in Neurogenic Bladder Dysfunction: Current and Future Perspectives.

Katarina Topoliova1,2, Stefan Harsanyi1,3, Lubos Danisovic1,3,4

  • 1National Institute of Rheumatic Diseases, Nabrezie I. Krasku 4, 921 12 Piestany, Slovakia.

Medicina (Kaunas, Lithuania)
|August 26, 2023
PubMed
Summary

Tissue engineering (TE) shows promise for neurogenic bladder dysfunction, but clinical translation is slow. More standardized research is needed to overcome current limitations in stem cell therapies.

Keywords:
bladder dysfunctionneurogenic bladderstem celltissue engineering

More Related Videos

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
04:05

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

346
Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder
06:18

Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder

Published on: May 23, 2020

3.9K

Related Experiment Videos

Last Updated: Jul 18, 2025

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.3K
Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
04:05

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

346
Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder
06:18

Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder

Published on: May 23, 2020

3.9K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Urology

Background:

  • Neurogenic bladder dysfunction presents significant challenges unmet by conventional treatments.
  • Tissue engineering (TE) offers a promising alternative approach for bladder repair and regeneration.

Purpose of the Study:

  • To review the current preclinical and clinical landscape of TE for neurogenic bladder.
  • To identify limitations and future directions for TE in treating neurogenic bladder dysfunction.

Main Methods:

  • Comprehensive literature review of preclinical and clinical studies on TE and stem cell therapies for neurogenic bladder.
  • Analysis of research trends, therapeutic strategies, and translational challenges.

Main Results:

  • Preclinical studies demonstrate significant potential for TE and stem cell therapies.
  • A major bottleneck is the slow translation from preclinical findings to clinical application.
  • Existing research suffers from a lack of standardization and limited investigation into non-spinal cord injury neurogenic causes.

Conclusions:

  • Tissue engineering holds considerable promise for neurogenic bladder dysfunction.
  • Standardization of research methods and further investigation into diverse etiologies are crucial for clinical advancement.