Biosensing Systems Based on Graphene Oxide Fluorescence Quenching Effect

Area of Science:

• Materials Science
• Nanotechnology
• Biomedical Engineering

Background:

• Graphene oxide (GO) is derived from graphite oxidation.
• GO exhibits unique fluorescence-modifying properties.
• These properties are useful for developing sensitive detection platforms.

Purpose of the Study:

• To review recent applications of GO-based fluorescence sensing systems.
• To highlight GO's role in switch-ON/OFF biosensors.
• To discuss GO's potential in diagnostics and therapeutics.

Main Methods:

• Literature review of GO-based fluorescence sensing.
• Analysis of GO's fluorescence quenching effect.
• Exploration of GO applications in biosensing platforms.

Main Results:

• GO significantly alters fluorophore fluorescence.
• GO enables switch-ON/OFF fluorescence biosensing.
• Applications include detection of biomolecules, pathogens, and contaminants.

Conclusions:

• GO-based sensing systems offer advanced diagnostic and therapeutic strategies.
• The fluorescence quenching effect of GO is a key mechanism.
• GO shows promise for detecting various pathologies and environmental issues.