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Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies
Sofia M Saraiva1, Telma A Jacinto1, Ana C Gonçalves2
1CPIRN-UDI/IPG, Center of Potential and Innovation of Natural Resources, Research Unit for Inland Development (UDI), Polytechnic Institute of Guarda, 6300-559 Guarda, Portugal.
Caffeine, a natural stimulant, offers antioxidant and anti-inflammatory benefits. Research explores its potential in disease prevention, neuroprotection, and sports performance, with new delivery methods enhancing its effects.
Area of Science:
- Biochemistry
- Pharmacology
- Human Physiology
Background:
- Caffeine is a widely consumed natural alkaloid with stimulant, antioxidant, and anti-inflammatory properties.
- Found in coffee, tea, and medications, its global consumption necessitates understanding its physiological impacts.
- Extensive research investigates caffeine's potential in disease prevention, anti-aging, and neuroprotection.
Purpose of the Study:
- To review caffeine's multifaceted effects on human health.
- To explore its role in managing cancer, cardiovascular, immunological, inflammatory, and neurological diseases.
- To discuss caffeine's application in sports and advancements in nanocarrier-based delivery systems.
Main Methods:
- Literature review of scientific studies on caffeine's biological activities.
- Analysis of research on caffeine's impact on various disease models.
- Examination of studies related to caffeine in athletic performance and novel formulations.
Main Results:
- Caffeine exhibits diverse pharmacological effects, including stimulant, antioxidant, and anti-inflammatory actions.
- Evidence suggests caffeine's potential benefits in preventing or managing several chronic diseases.
- Research highlights caffeine's ergogenic effects and the promise of nanocarrier systems for improved bioavailability.
Conclusions:
- Caffeine possesses significant therapeutic potential across a range of health conditions.
- Further research into caffeine's mechanisms and optimized delivery is warranted.
- Caffeine's role in disease management and performance enhancement is a dynamic field of study.
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