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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Restoration of Life Expectancy After Transcatheter Edge-to-Edge Mitral Valve Repair
Luigi Biasco1, Catherine Klersy2, Giovanni Benfari3
1Department of Biomedical Sciences, University of Italian Switzerland, Lugano, Switzerland; Azienda Sanitaria Locale Torino 4, Ciriè, Turin, Italy.
JACC. Cardiovascular Interventions
|August 26, 2023
Summary
Mitral transcatheter edge-to-edge repair (TEER) can restore life expectancy in elderly patients, especially those with primary mitral regurgitation. Successful repair significantly improves survival rates, highlighting the importance of sustained reduction in mitral regurgitation.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Economics
Background:
- Survival data following mitral transcatheter edge-to-edge repair (TEER) are limited.
- The impact of TEER on predicted life expectancy remains largely unknown.
Purpose of the Study:
- To estimate the effect of TEER on postprocedural life expectancy using relative survival (RS) analysis.
- To assess 5-year survival and RS after TEER in patients aged 60-89.
Main Methods:
- Analysis of 1140 consecutive TEER patients (2011-2018) from the Swiss MitraSwiss registry.
- Calculation of RS by comparing post-TEER survival to expected survival using Swiss national mortality tables.
- Assessment of RS based on mitral regurgitation etiology, age group, and procedural success.
Main Results:
- Overall 5-year survival after TEER was 59.3%, with an RS of 80.5%.
- RS was higher in primary mitral regurgitation (91.1%) compared to secondary mitral regurgitation (71.5%).
- Patients aged 80-89 showed a 5-year RS of 93.0%, with PMR patients achieving 100% RS.
Conclusions:
- Mitral TEER can restore predicted life expectancy in elderly patients (80-89 years) with primary mitral regurgitation.
- Sustained procedural success in secondary mitral regurgitation also demonstrated high relative survival.
- Successful and sustained reduction of mitral regurgitation is crucial for improving survival, particularly in older patients.
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