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LRRK2 aggravates kidney injury through promoting MFN2 degradation and abnormal mitochondrial integrity

Shun Zhang1, Subo Qian1, Hailong Liu1

  • 1Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.

Redox Biology
|August 26, 2023
PubMed

Keywords:
Acute kidney injury (AKI)Chronic kidney disease (CKD)Leucine-rich repeat kinase 2 (LRRK2)Mitochondrial damagesMitofusin 2 (MFN2)Proximal tubular cell (PTC)

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