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Preparation of Intact Bovine Tail Intervertebral Discs for Organ Culture
Published on: February 2, 2012
Effect of DiscoGel treatment of the intervertebral disc at MRI
K Latka1, K Kozlowska2, M Waligora3
1Department of Neurosurgery, University Hospital in Opole, 45-001, 26 Witosa Ave., Opole, Poland.
Aim:
To determine the impact of ethanol gel chemonucleolysis (EGCh) on the radiological picture of the treated intervertebral disc, the relationship between the initial radiological status and the clinical status of the patient after EGCh treatment, and the optimal radiographic criteria for qualifying a patient for EGCh treatment.
Materials And Methods:
The study involved a group of 45 patients (25 men and 20 women) aged 23-68 years (46 ± 11) who underwent an EGCh procedure after qualification, radiography, and clinical questionnaire evaluation.
Results:
The results showed a decrease in the size of the protrusion and Gadolinium-Enhanced (GI) zone in the treated intervertebral disc. The presence of a high-intensity zone (HIZ) on baseline magnetic resonance imaging was found to be a good predictor of the timing and outcome of treatment, and an increase in disc height was observed in adjacent segments.
Conclusion:
These findings suggest that EGCh is a promising treatment for spine diseases, and the HIZ on baseline magnetic resonance imaging can be used as a qualification criterion for this procedure.
