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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Fungal Phylum Ascomycota01:28

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Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Related Experiment Video

Updated: Jul 18, 2025

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
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Relationship between Aspergillus and asthma.

Ritesh Agarwal1, Valliappan Muthu1, Inderpaul Singh Sehgal1

  • 1Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Allergology International : Official Journal of the Japanese Society of Allergology
|August 26, 2023
PubMed
Summary

Fungal sensitization, particularly Aspergillus fumigatus, significantly impacts severe asthma control. This review details fungal asthma diagnosis and treatment, including allergic fungal airway disease.

Keywords:
ABPAAllergic bronchopulmonary mycosisBronchiectasisCystic fibrosisFungal asthma

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Area of Science:

  • Pulmonology
  • Allergology
  • Mycology

Background:

  • Fungal sensitization is common in severe asthma.
  • Aspergillus fumigatus (A. fumigatus) is a key factor due to its properties and allergens.
  • Fungal asthma presents diverse symptoms, making diagnosis challenging.

Purpose of the Study:

  • To review the association between Aspergillus and asthma.
  • To discuss diagnostic approaches for fungal asthma entities.
  • To evaluate newer definitions like allergic fungal airway disease and current treatments.

Main Methods:

  • Literature review of relevant studies on Aspergillus and asthma.
  • Analysis of diagnostic criteria including clinical history, immunological tests, and imaging.
  • Synthesis of current treatment strategies for fungal asthma.

Main Results:

  • A. fumigatus exacerbates asthma control through allergens and conidia.
  • Diagnosis requires integrated assessment of clinical, immunological, and imaging data.
  • Personalized treatment includes standard asthma medications and antifungal therapy.

Conclusions:

  • Fungal asthma diagnosis and management are complex.
  • Newer definitions may refine understanding and treatment of fungal airway diseases.
  • Comprehensive management is crucial for patients with fungal sensitization and asthma.