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Cognitive changes associated with cerebral emboli during coronary intervention.

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    Bratislavske Lekarske Listy
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    Elective coronary interventions carry a high risk of cerebral embolism, detected via transcranial Doppler (TCD). More microembolic signals (MES) correlate with cognitive decline after the procedure.

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    Area of Science:

    • Neuroscience
    • Cardiology
    • Radiology

    Background:

    • Cerebral embolism is a risk during coronary interventions.
    • Microembolic signals (MES) can be detected using transcranial Doppler (TCD).
    • Silent strokes and cognitive dysfunction are potential consequences.

    Purpose of the Study:

    • Investigate factors influencing MES frequency and type during coronary interventions.
    • Correlate MES with silent stroke on MRI and cognitive dysfunction.

    Main Methods:

    • 70 patients undergoing elective coronary interventions were monitored using TCD.
    • Neurologic exams and brain MRI were performed pre- and post-intervention.
    • Cognitive function tests were administered pre- and post-intervention.

    Main Results:

    • 94.3% of patients had detectable MES.
    • 25.7% showed new asymptomatic ischemic lesions on MRI.
    • Increased solid MES and combined solid/gaseous MES correlated with cognitive decline (ACE-R, MMSE).

    Conclusions:

    • Cardiac catheterization poses a significant risk of cerebral embolism.
    • Higher MES counts are linked to cognitive deterioration post-intervention.