[Structural mechanisms for the realization of the secretory activity of human endocrine organs in prenatal...

A study was made of the secretory active cells and intraorganic blood channel of the hypophysis, thyroid, thymus, ovaries and testes and human embryos and fetuses of 4-5 week -9 mos intrauterine development. The development of the hematocellular barriers in the human endocrine organs during the period of intrauterine development was studied from the view-point of the expression of their secretory activity. The time course of the transmission of endocrine information in the endocrine glands during prenatal morphogenesis determined by the phases of the development of transport communications of the microcirculatory system was studied. The system of contact means of the transmission of the secretory material was the first to function in the endocrine glands in the prenatal period of morphogenesis. The structural-functional formation and development of the microcirculatory system was a morphological base for the expression of the long- and short-distant means of the transmission of the secretory material to target cells and organs.