Kimura Disease-A Case Report
Abhijeet Bhatia1, Subhadeep Das1, Anuradha Deka1
1Department of ENT, NEIGRIHMS, Shillong, 793018 India.
Summary
Kimura disease, a rare eosinophilic disorder, typically affects young males with swelling and enlarged glands. Management involves surgery, steroids, and sometimes chemotherapy, but recurrence is common.
Area of Science:
- Immunology
- Pathology
- Radiology
Background:
- Kimura disease is an idiopathic, eosinophilic, hyperplastic, and granulomatous condition.
- It predominantly affects young males, presenting with subcutaneous swelling, salivary gland enlargement, and lymphadenopathy.
Purpose of the Study:
- To provide a comprehensive overview of Kimura disease.
- To discuss diagnostic criteria, imaging, and management strategies.
- To highlight the challenges in managing recurrence.
Main Methods:
- Diagnosis relies on histopathological examination.
- Key indicators include elevated serum IgE and hypereosinophilia.
- Magnetic Resonance Imaging (MRI) is the preferred radiological investigation.
Main Results:
- The disease is characterized by specific histopathological findings.
- Biochemical markers like IgE and eosinophil counts are significantly elevated.
- MRI provides detailed visualization for diagnosis and monitoring.
Conclusions:
- Kimura disease requires a multi-faceted diagnostic approach combining clinical, biochemical, and imaging data.
- Treatment strategies encompass surgical excision, corticosteroid therapy, and potentially chemotherapy.
- Despite treatment, the disease has a notable tendency for relapse and recurrence, necessitating long-term follow-up.
Keywords:
Angiolymphatic proliferationEosinophilic microabscessHypereosinophiliaKimura DiseaseRaised serum IgE
