Microbial Etiologies of Otitis Media with Resistance Pattern in a Tertiary Care Hospital in North India

Kajal Gupta1, Dakshina Bisht2, Suneel Bhooshan3

  • 1Department of Microbiology, RKDF MCH & RC Bhopal, Bhopal, MP India.

Abstract

Insights

This study identified common bacteria and fungi in ear infections like Acute Otitis Media (AOM) and Chronic Otitis Media (COM). Fluoroquinolones showed the highest effectiveness against these microbes, suggesting targeted antibiotic use can combat resistance.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Otitis Media (OM), encompassing Acute Otitis Media (AOM) and Chronic Otitis Media (COM), is a common condition often associated with microbial infections.
  • Understanding the specific bacterial and fungal pathogens and their antibiotic sensitivities is crucial for effective treatment and managing antimicrobial resistance.

Purpose of the Study:

  • To determine the prevalent bacterial and fungal species causing OM, AOM, and COM.
  • To assess the antibiotic sensitivity patterns of isolated microorganisms in a hospital setting.

Main Methods:

  • Cultured microbial flora from ear discharge swabs of 150 clinically diagnosed OM patients.
  • Performed drug susceptibility testing using the Kirby-Bauer disc diffusion method.

Main Results:

  • Streptococcus spp. were most frequently isolated in AOM, while Staphylococcus aureus was dominant in COM.
  • Candida albicans was the predominant fungal isolate.
  • Organisms exhibited maximum sensitivity to Fluoroquinolones.

Conclusions:

  • Accurate diagnosis of ear infections is essential for appropriate treatment.
  • Judicious antibiotic prescription is key to reducing the burden of antibiotic resistance.

Related Concept Videos

Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
38
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
303
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.3K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
385
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
268