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Published on: August 28, 2018
Calcification detection on upper extremity arteries: a comparison of ultrasonic and X-ray methods
Yanli Yang1, Na Lin1, Yuankai Xu2
1Department of Nephrology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Insights
Ultrasound is more sensitive than X-ray for detecting vascular calcification (VC) in hemodialysis patients
Area of Science:
- Vascular Biology
- Medical Imaging
- Nephrology
Background:
- Vascular calcification (VC) is a known complication in hemodialysis patients.
- Limited research exists on upper extremity vascular calcification in this population.
- Consistency between ultrasound and X-ray for detecting VC is not well-established.
Purpose of the Study:
- To determine the prevalence of VC in the radial and ulnar arteries of hemodialysis patients.
- To assess the consistency of VC detection between ultrasound and X-ray imaging.
Main Methods:
- 40 hemodialysis patients underwent both ultrasound and X-ray examinations of their upper extremity arteries.
- Calcification was quantified using a calcification index from each imaging modality.
- Clinical data were collected for all participants.
Main Results:
- Ultrasound detected VC in 31 patients, while X-ray detected it in 22 patients.
- X-ray showed 73.21% sensitivity and 66.35% specificity compared to ultrasound.
- Agreement between ultrasound and X-ray was fair; ulnar arteries showed more VC than radial arteries.
Conclusions:
- Ultrasound demonstrates higher sensitivity for detecting calcified atherosclerotic lesions.
- Ultrasound and X-ray show fair consistency in VC detection.
- Ultrasound screening of upper extremity arteries in hemodialysis patients warrants further investigation.
Background:
Vascular calcification (VC) has been observed in patients with hemodialysis, whereas few studies have investigated calcification in the upper extremity vasculature. Both ultrasound and X-ray are used to investigate the calcification of arteries in patients. However, there is a lack of data on the consistency between these two methods. The aim of this study was to investigate the occurrence of VC in the radial and ulnar arteries of hemodialysis patients and investigate the detection consistency in VC between ultrasound and X-ray.
Methods:
Ultrasound and X-ray examinations were performed in the radial and ulnar arteries of both the left and right upper extremities of 40 patients on hemodialysis. The calcification status of arteries was evaluated by the calcification index from ultrasound and X-ray respectively. Clinical variables of patients were collected from all the involved patients.
Results:
Of the 40 patients, VC was detected in 31 patients by ultrasound, while X-ray detected VC in 22 patients. Compared to ultrasound assessment, X-ray assessment was 73.21% sensitive but only 66.35% specific with a positive predictive value of 53.95% for detecting calcifications in the radial or ulnar artery. The level of agreement between ultrasound and X-ray results was fair. In addition, our data showed that more ulnar arteries had VCs than the corresponding radial arteries.
Conclusion:
Ultrasound is more sensitive in detecting the presence of calcified atherosclerotic lesions. Ultrasound and X-ray exhibited fair consistency. Ultrasound screening for upper extremity radial and ulnar arteries in hemodialysis patients may deserve attention to explore its clinical significance.
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